Puas yog txhua yam ntawm Down syndrome vim yog Nondisjunction?

2024 Tus sau: Edward Hancock | [email protected]. Kawg hloov kho: 2023-12-16 01:32

Puas muaj Ntau hom Down Syndrome ? Down syndrome feem ntau yog tshwm sim los ntawm kev ua yuam kev hauv cell division hu ua kev tsis sib haum xeeb .” Kev tsis sib haum xeeb ua rau lub embryo nrog peb daim ntawv theej ntawm chromosome 21 es tsis txhob ntawm ob li niaj zaus. Qhov no hom mob Down syndrome , uas suav rau 95% ntawm cov neeg mob, hu ua trisomy 21.

Ib yam li ntawd, puas yog Down syndrome tshwm sim los ntawm kev tsis sib haum xeeb hauv meiosis 1 lossis 2?

Kev tsis sib haum xeeb tshwm sim thaum homologous chromosomes ( meiosis Kuv) los yog tus muam chromatids ( meiosis II ) tsis cais thaum lub sij hawm meiosis . Feem ntau trisomy yog chromosome 21, uas ua rau Down syndrome.

Kuj Paub, puas muaj daim ntawv me me ntawm Down syndrome? Tus me nyuam nrog Down syndrome tuaj yeem yug tau qhov loj me, tab sis yuav loj hlob qeeb dua li tus menyuam tsis muaj mob. Cov neeg nrog Down syndrome feem ntau muaj qee qhov kev loj hlob tsis taus, tab sis feem ntau nws yog mob me mus rau nruab nrab.

Kuj nug, puas muaj qhov sib txawv ntawm Down syndrome?

Nyob ntawd yog peb hom mob Down syndrome : trisomy 21 (nondisjunction), translocation thiab mosaicism. Trisomy 21, feem ntau hom ntawm Down syndrome , tshwm sim thaum nyob ntawd yog peb, ntau dua li ob, tus lej 21 chromosomes muaj nyob hauv txhua lub cell ntawm lub cev. Translocation tso nyiaj rau 4% ntawm tag nrho cov xwm txheej ntawm Down syndrome.

Dab tsi yog 3 kab mob vim Nondisjunction?

Nondisjunction: Ua tsis tiav ntawm khub chromosomes cais (kom disjoin) thaum lub sij hawm cell division, kom ob leeg chromosomes mus rau ib tug ntxhais cell thiab tsis mus rau lwm yam. Nondisjunction ua rau yuam kev hauv chromosome tooj, xws li trisomy 21 ( Down syndrome ) thiab monosomy X ( Turner Syndrome ).