Papp A theem thaum cev xeeb tub yog dab tsi?
Papp A theem thaum cev xeeb tub yog dab tsi?

Video: Papp A theem thaum cev xeeb tub yog dab tsi?

Video: Papp A theem thaum cev xeeb tub yog dab tsi?
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Tshwj xeeb tshaj yog, tsawg leej niam cov ntshav cev xeeb tub-kwv yees plasma protein -A ( PAPP -A), ntawm 11-13 lub lis piam ntawm cev xeeb tub, cuam tshuam nrog kev yug menyuam, kev tuag ntawm tus menyuam mos, kev txwv kev loj hlob ntawm lub tsev menyuam, kev yug menyuam ntxov, thiab ua ntej eclampsia hauv chromosomally ib txwm fetuses, thaum lub sijhawm nce nuchal translucency yog txuam nrog tshwj xeeb.

Tib neeg kuj nug, dab tsi yog PAPP qis ib theem thaum cev xeeb tub?

Qib qis ntawm PAPP -A (thaum nws tsawg dua 0.4 MoM hauv cev xeeb tub ) tej zaum yuav cuam tshuam nrog: Tus me nyuam yug los qis dua vim tias koj cov placenta yuav tsis ua haujlwm zoo li. Muaj kev pheej hmoo ntawm kev yug ntxov. Miscarriage nyob rau hauv lub thib ob ib nrab ntawm cev xeeb tub.

Qhov thib ob, Pappa txhais li cas thaum cev xeeb tub? Kev xeeb tub -associated plasma protein A: Abbreviated as PAPPA los yog PAPP-A. Ib tug loj zinc-binding protein uas ua raws li ib tug enzyme, tshwj xeeb tshaj yog ib tug metallopeptidase. Lub gene rau PAPPA yog nyob rau hauv chromosome band 9q33. 1. PAPPA tau siv nyob rau hauv cev xeeb tub Kev tshuaj ntsuam genetic thiab kev tshawb fawb ntawm atherosclerosis.

Ib yam li ntawd, Papp A nce ntxiv thaum cev xeeb tub?

PAPP -Ib theem nce thoob plaws ib txwm cev xeeb tub nyob rau hauv trisomy 21, PAPP -Ib theem tau txo qis, tab sis tsuas yog thaum tus thawj peb lub hlis twg . PAPP -Ib theem tau txo qis hauv trisomy 13 thiab sharply hauv trisomy 18, txawm lub hnub nyoog gestational.

Dab tsi yog qhov dawb beta hCG qib thaum cev xeeb tub?

Thaum muaj kev sib deev chromosomal anomalies, niam txiv dawb β- hCG yog ib txwm thiab PAPP-A yog qis [46]. Hauv trisomy 21 cev xeeb tub qhov nruab nrab MoM dawb β- hCG nce los ntawm 1.8 ntawm 11 lub lis piam mus rau 2.09 ntawm 13 lub lis piam, thiab feem ntau tus nqi rau PAPP-A yog 0.38 thiab 0.65 MoMs.

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